Nissim Benvenisty lab

Selected publications:

2017

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Human pluripotent stem cells in modeling human disorders: the case of fragile X syndrome. Vershkov D, Benvenisty N.
Regen Med. 2017 Jan;12(1):53-68.

2016

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Stem cells: Aspiring to naivety. Sagi I, Benvenisty N.
Nature. 2016 Dec 8;540(7632):211-212.

   
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Identification and propagation of haploid human pluripotent stem cells. Sagi I, Egli D, Benvenisty N.
Nat Protoc. 2016 Nov;11(11):2274-2286.

   
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Haploid Human Embryonic Stem Cells: Half the Genome, Double the Value. Yilmaz A, Peretz M, Sagi I, Benvenisty N.
Cell Stem Cell. 2016 Nov 3;19(5):569-572.

   
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Molecular Characterization of Down Syndrome Embryonic Stem Cells Reveals a Role for RUNX1 in Neural Differentiation. Halevy T, Biancotti JC, Yanuka O, Golan-Lev T, Benvenisty N.
Stem Cell Reports. 2016 Oct 11;7(4):777-786.

   
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Chromosomal Instability and Molecular Defects in Induced Pluripotent Stem Cells from Nijmegen Breakage Syndrome Patients. Halevy T, Akov S, Bohndorf M, Mlody B, Adjaye J, Benvenisty N, Goldberg M.
Cell Rep. 2016 Aug 30;16(9):2499-511.

   
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Efficient Generation of Viral and Integration-Free Human Induced Pluripotent Stem Cell-Derived Oligodendrocytes. Espinosa-Jeffrey A, Blanchi B, Biancotti JC, Kumar S, Hirose M, Mandefro B, Talavera-Adame D, Benvenisty N, de Vellis J.
Curr Protoc Stem Cell Biol. 2016 Aug 17.

   
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Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq. Weissbein U, Schachter M, Egli D, Benvenisty N.
Nat Commun. 2016 Jul 7;7:12144.

   
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iPSCs: 10 Years and Counting.
Cell. 2016 May 19;165(5):1041-2.

   
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New ISSCR guidelines: clinical translation of stem cell research. Kimmelman J, Heslop HE, Sugarman J, Studer L, Benvenisty N, Caulfield T, Hyun I, Murry CE, Sipp D, Daley GQ.
Lancet. 2016 May 14;387(10032):1979-81.

   
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Setting Global Standards for Stem Cell Research and Clinical Translation: The 2016 ISSCR Guidelines. Daley GQ, Hyun I, Apperley JF, Barker RA, Benvenisty N, Bredenoord AL, Breuer CK, Caulfield T, Cedars MI, Frey-Vasconcells J, Heslop HE, Jin Y, Lee RT, McCabe C, Munsie M, Murry CE, Piantadosi S, Rao M, Rooke HM, Sipp D, Studer L, Sugarman J, Takahashi M, Zimmerman M, Kimmelman J.
Stem Cell Reports. 2016 May 12.

   
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Policy: Global standards for stem-cell research. Kimmelman J, Hyun I, Benvenisty N, Caulfield T, Heslop HE, Murry CE, Sipp D, Studer L, Sugarman J, Daley GQ.
Nature. 2016 May 12;533(7603):311-3.

   
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Derivation and differentiation of haploid human embryonic stem cells. Sagi I, Chia G, Golan-Lev T, Peretz M, Weissbein U, Sui L, Sauer MV, Yanuka O, Egli D, Benvenisty N.
Nature. 2016 Mar 16.

   
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Pluripotent stem cells in disease modelling and drug discovery. Avior Y, Sagi I, Benvenisty N.
Nat Rev Mol Cell Biol. 2016 Mar;17(3):170-82.

   
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Genomic Instability in Human Pluripotent Stem Cells Arises from Replicative Stress and Chromosome Condensation Defects. Lamm N, Ben-David U, Golan-Lev T, Storchová Z, Benvenisty N, Kerem B.
Cell Stem Cell. 2016 Feb 4;18(2):253-61.

2015

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Reversion of FMR1 Methylation and Silencing by Editing the Triplet Repeats in Fragile X iPSC-Derived Neurons. Park CY, Halevy T, Lee DR, Sung JJ, Lee JS, Yanuka O, Benvenisty N, Kim DW.
Cell Rep. 2015 Sep 29.

   
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Hallmarks of pluripotency. De Los Angeles A, Ferrari F, Xi R, Fujiwara Y, Benvenisty N, Deng H, Hochedlinger K, Jaenisch R, Lee S, Leitch HG, Lensch MW, Lujan E, Pei D, Rossant J, Wernig M, Park PJ, Daley GQ.
Nature. 2015 Sep 24;525(7570):469-78.

   
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rsPSCs: A new type of pluripotent stem cells. Weissbein U, Benvenisty N.
Cell Res. 2015 Aug;25(8):889-90.

   
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TeratoScore: Assessing the Differentiation Potential of Human Pluripotent Stem Cells by Quantitative Expression Analysis of Teratomas. Avior Y, Biancotti JC, Benvenisty N.
Stem Cell Reports. 2015 Jun 9;4(6):967-74.

   
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Differentiation of human parthenogenetic pluripotent stem cells reveals multiple tissue- and isoform-specific imprinted transcripts. Stelzer Y, Bar S, Bartok O, Afik S, Ronen D, Kadener S, Benvenisty N.
Cell Rep. 2015 Apr 14;11(2):308-20.

   
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Molecular mechanisms regulating the defects in fragile X syndrome neurons derived from human pluripotent stem cells. Halevy T, Czech C, Benvenisty N.
Stem Cell Reports. 2015 Jan 13;4(1):37-46.

   
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Brief Reports: Controlling the Survival of Human Pluripotent Stem Cells by Small Molecule-Based Targeting of Topoisomerase II Alpha. Ben-David U, Cowell IG, Austin CA, Benvenisty N.
Stem Cells. 2015 Mar;33(3):1013-9.

   

2014

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Virtual karyotyping reveals greater chromosomal stability in neural cells derived by transdifferentiation than those from stem cells. Weissbein U, Ben-David U, Benvenisty N.
Cell Stem Cell. 2014 Dec 4;15(6):687-91.

   
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Comparable frequencies of coding mutations and loss of imprinting in human pluripotent cells derived by nuclear transfer and defined factors. Johannesson B, Sagi I, Gore A, Paull D, Yamada M, Golan-Lev T, Li Z, LeDuc C, Shen Y, Stern S, Xu N, Ma H, Kang E, Mitalipov S, Sauer MV, Zhang K, Benvenisty N, Egli D.
Cell Stem Cell. 2014 Nov 6;15(5):634-42.

   
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Aneuploidy induces profound changes in gene expression, proliferation and tumorigenicity of human pluripotent stem cells. Ben-David U, Arad G, Weissbein U, Mandefro B, Maimon A, Golan-Lev T, Narwani K, Clark AT, Andrews PW, Benvenisty N, Carlos Biancotti J.
Nat Commun. 2014 Sep 8;5:4825.

   
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Sex-dependent gene expression in human pluripotent stem cells. Ronen D, Benvenisty N.
Cell Rep. 2014 Aug 21;8(4):923-32.

   
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Aberrant DNA Methylation in ES Cells. Ludwig G, Nejman D, Hecht M, Orlanski S, Abu-Remaileh M, Yanuka O, Sandler O, Marx A, Roberts D, Benvenisty N, Bergman Y, Mendelsohn M, Cedar H.
PLoS One. 2014 May 22;9(5).

   
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The noncoding RNA IPW regulates the imprinted DLK1-DIO3 locus in an induced pluripotent stem cell model of Prader-Willi syndrome. Stelzer Y, Sagi I, Yanuka O, Eiges R, Benvenisty N.
Nat Genet. 2014 May 11.

   
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Human oocytes reprogram adult somatic nuclei of a type 1 diabetic to diploid pluripotent stem cells. Yamada M, Johannesson B, Sagi I, Burnett LC, Kort DH, Prosser RW, Paull D, Nestor MW, Freeby M, Greenberg E, Goland RS, Leibel RL, Solomon SL, Benvenisty N, Sauer MV, Egli D.
Nature. 2014 Apr 28.

   
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Elimination of undifferentiated cancer cells by pluripotent stem cell inhibitors. Ben-David U, Biran A, Scaffidi P, Herold-Mende C, Boehringer M, Meshorer E, Benvenisty N.
J Mol Cell Biol. 2014 Apr 16.

   
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Chemical ablation of tumor-initiating human pluripotent stem cells. Ben-David U, Benvenisty N.
Nat Protoc. 2014 Mar;9(3):729-40.

   
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Quality control: Genome maintenance in pluripotent stem cells. Weissbein U, Benvenisty N, Ben-David U.
J Cell Biol. 2014 Jan 20;204(2):153-63.

2013

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Global Indiscriminate Methylation in Cell-Specific Gene Promoters following Reprogramming into Human Induced Pluripotent Stem Cells. Nissenbaum J, Bar-Nur O, Ben-David E, Benvenisty N.
Stem Cell Reports. 2013 Dec 12;1(6):509-17.

   
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Involvement of parental imprinting in the antisense regulation of onco-miR-372-373. Stelzer Y, Sagi I, Benvenisty N.
Nat Commun. 2013;4:2724.

   
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Identification of novel imprinted differentially methylated regions by global analysis of human-parthenogenetic-induced pluripotent stem cells. Stelzer Y, Ronen D, Bock C, Boyle P, Meissner A, Benvenisty N.
Stem Cell Reports. 2013 Jun 4;1(1):79-89.

   
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Human pluripotent stem cells with distinct X inactivation status show molecular and cellular differences controlled by the X-Linked ELK-1 gene. Bruck T, Yanuka O, Benvenisty N.
Cell Rep. 2013 Jul 25;4(2):262-70.

   
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Immunologic and chemical targeting of the tight-junction protein Claudin-6 eliminates tumorigenic human pluripotent stem cells. Ben-David U, Nudel N, Benvenisty N.
Nat Commun. 2013;4:1992.

   
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New balance in pluripotency: reprogramming with lineage specifiers. Ben-David U, Nissenbaum J, Benvenisty N.
Cell. 2013 May 23;153(5):939-40.

   
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Analyzing the genomic integrity of stem cells. Ben-David U, Benvenisty N.
StemBook [Internet]. Cambridge (MA)

   
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Virtual karyotyping of pluripotent stem cells on the basis of their global gene expression profiles. Ben-David U, Mayshar Y, Benvenisty N.
Nat Protoc. 2013 May;8(5):989-97.

   
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Selective elimination of human pluripotent stem cells by an oleate synthesis inhibitor discovered in a high-throughput screen. Ben-David U, Gan QF, Golan-Lev T, Arora P, Yanuka O, Oren YS, Leikin-Frenkel A, Graf M, Garippa R, Boehringer M, Gromo G, Benvenisty N. Cell Stem Cell. 2013 Feb 7;12(2):167-79.

2012

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Genomic stability in reprogramming. Ronen D, Benvenisty N.
Curr Opin Genet Dev. 2012 Oct 3.

   
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DUXO, a novel double homeobox transcription factor, is a regulator of the gastrula organizer in human embryonic stem cells. Sharon N, Mor I, Zahavi E, Benvenisty N. Stem Cell Res. 2012 Aug 18;9(3):261-269.

   
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Reprogramming of the MHC-I and its Regulation by NFκB in Human Induced Pluripotent Stem Cells. Pick M, Ronen D, Yanuka O, Benvenisty N. Stem Cells. 2012 Sep 17.

   
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The in vitro survival of human monosomies and trisomies as embryonic stem cells. Biancotti JC, Narwani K, Mandefro B, Golan-Lev T, Buehler N, Hill D, Svendsen CN, Benvenisty N. Stem Cell Res. 2012 Jul 22;9(3):218-224.

   
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Expanding the boundaries of embryonic stem cells. Ben-David U, Kopper O, Benvenisty N. Cell Stem Cell. 2012 Jun 14;10(6):666-77.

   
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Targeting pancreatic progenitor cells in human embryonic stem cell differentiation for the identification of novel cell surface markers. Fishman B, Segev H, Kopper O, Nissenbaum J, Schulman M, Benvenisty N, Itskovitz-Eldor J, Kitsberg D. Stem Cell Rev. 2012 Sep;8(3):792-802

   
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Molecular analysis of FMR1 reactivation in fragile-X induced pluripotent stem cells and their neuronal derivatives. Bar-Nur O, Caspi I, Benvenisty N. J Mol Cell Biol. 2012 Apr 19.

   
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High Prevalence of Evolutionarily-conserved and Species-Specific Genomic Aberrations in Mouse Pluripotent Stem Cells. Ben-David U, Benvenisty N. Stem Cells. 2012 Feb 10.

2011

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Stepwise differentiation of human embryonic stem cells into early endoderm derivatives and their molecular characterization. Kopper O, Benvenisty N. Stem Cell Res. 2011 Dec 21;8(3):335-345.

   
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Significant Acquisition of Chromosomal Aberrations in Human Adult Mesenchymal Stem Cells Ben-David U, Mayshar Y, Benvenisty N. Cell Stem Cell. 2012 Jan 6;10(1):10-1.

   
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Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage. The International Stem Cell Initiative. Nat Biotechnol. 2011 Nov 27.

 
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Large-scale analysis reveals acquisition of lineage-specific chromosomal aberrations in human adult stem cells. Ben-David U, Mayshar Y, Benvenisty N. Cell Stem Cell. 2011 Aug 5;9(2):97-102.

 
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Aneuploid human embryonic stem cells: origins and potential for modeling chromosomal disorders. Biancotti JC, Benvenisty N. Regen Med. 2011 Jul;6(4):493-503.

 
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Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet Beta cells. Bar-Nur O, Russ HA, Efrat S, Benvenisty N. Cell Stem Cell. 2011 Jul 8;9(1):17-23.

 
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Assessing the safety of stem cell therapeutics. Goldring CE, Duffy PA, Benvenisty N, Andrews PW, Ben-David U, Eakins R, French N, Hanley NA, Kelly L, Kitteringham NR, Kurth J, Ladenheim D, Laverty H, McBlane J, Narayanan G, Patel S, Reinhardt J, Rossi A, Sharpe M, Park BK. Cell Stem Cell. 2011 Jun 3;8(6):618-28.

 
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Global analysis of parental imprinting in human parthenogenetic induced pluripotent stem cells. Stelzer Y, Yanuka O, Benvenisty N. Nat Struct Mol Biol. 2011 May 15.

 
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The tumorigenicity of human embryonic and induced pluripotent stem cells. Ben-David U, Benvenisty N. Nat Rev Cancer. 2011 Apr;11(4):268-77.

   
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Molecular and Functional Characterization of Gastrula Organizer Cells Derived from Human Embryonic Stem Cells. Sharon N, Mor I, Golan-Lev T, Fainsod A, Benvenisty N.
Stem Cells. 2011 Feb 15.

   
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Publishing SNP Genotypes of Human Embryonic Stem Cell Lines: Policy Statement of the International Stem Cell Forum Ethics Working Party. Knoppers BM, Isasi R, Benvenisty N, Kim OJ, Lomax G, Morris C, Murray TH, Lee EH, Perry M, Richardson G, Sipp D, Tanner K, Wahlström J, de Wert G, Zeng F. Stem Cell Rev. 2011 Jan 29.

   
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Meta-analysis of the heterogeneity of X chromosome inactivation in human pluripotent stem cells. Bruck T, Benvenisty N. Stem Cell Res. 2011 Mar;6(2):187-93.

2010

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Genetic instability in human induced pluripotent stem cells: classification of causes and possible safeguards. Ben-David U, Benvenisty N, Mayshar Y.
Cell Cycle. 2010 Dec 1;9(23):4603-4.

   
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Identification and classification of chromosomal aberrations in human induced pluripotent stem cells. Mayshar Y, Ben-David U, Lavon N, Biancotti JC, Yakir B, Clark AT, Plath K, Lowry WE, Benvenisty N. Cell Stem Cell. 2010 Oct 8;7(4):521-31.

   
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Benefits of utilizing gene-modified iPSCs for clinical applications. Ellis J, Baum C, Benvenisty N, Mostoslavsky G, Okano H, Stanford WL, Porteus M, Sadelain M.
Cell Stem Cell. 2010 Oct 8;7(4):429-30.

   
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Human embryonic stem cells as models for aneuploid chromosomal syndromes. Biancotti JC, Narwani K, Buehler N, Mandefro B, Golan-Lev T, Yanuka O, Clark A, Hill D, Benvenisty N, Lavon N. Stem Cells. 2010 Sep;28(9):1530-40.

   
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Teratogen Screening Using Transcriptome Profiling of Differentiating Human Embryonic Stem Cells. Mayshar Y, Yanuka O, Benvenisty N. J Cell Mol Med. 2010 Jun 17.

   
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Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells. Urbach A, Bar-Nur O, Daley GQ, Benvenisty N.
Cell Stem Cell. 2010 May 7;6(5):407-11.

   
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High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity. Närvä E, Autio R, Rahkonen N, Kong L, Harrison N, Kitsberg D, Borghese L, Itskovitz-Eldor J, Rasool O, Dvorak P, Hovatta O, Otonkoski T, Tuuri T, Cui W, Brüstle O, Baker D, Maltby E, Moore HD, Benvenisty N, Andrews PW, Yli-Harja O, Lahesmaa R. Nat Biotechnol. 2010 Apr;28(4):371-7.

   
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Human embryonic stem cells from aneuploid blastocysts identified by pre-implantation genetic screening. Narwani K, Biancotti JC, Golan-Lev T, Buehler N, Hill D, Shifman S, Benvenisty N, Lavon N. In Vitro Cell Dev Biol Anim. 2010 Apr;46(3-4):309-16.

   
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Human ES cell lines--introduction. Andrews PW, Benvenisty N, Knowles BB, McKay RD, Oh SK, Pera MF, Rossant J, Stacey GN. In Vitro Cell Dev Biol Anim. 2010 Apr;46(3-4):167-8.

   
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Comparison of defined culture systems for feeder cell free propagation of human embryonic stem cells. International Stem Cell Initiative Consortium, In Vitro Cell Dev Biol Anim. 2010 Apr;46(3-4):247-58.

2009

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Cell lines derived from human parthenogenetic embryos can display aberrant centriole distribution and altered expression levels of mitotic spindle check-point transcripts. Brevini TA, Pennarossa G, Antonini S, Paffoni A, Tettamanti G, Montemurro T, Radaelli E, Lazzari L, Rebulla P, Scanziani E, de Eguileor M, Benvenisty N, Ragni G, Gandolfi F. Stem Cell Rev. 2009 Dec;5(4):340-52.

   
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Consensus guidance for banking and supply of human embryonic stem cell lines for research purposes. International Stem Cell Banking Initiative. Stem Cell Rev. 2009 Dec;5(4):301-14.

   
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Characterization of gastrulation-stage progenitor cells and their inhibitory crosstalk in human embryoid bodies. Kopper O, Giladi O, Golan-Lev T, Benvenisty N.
Stem Cells. 2010 Jan;28(1):75-83.

   
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The tumorigenicity of diploid and aneuploid human pluripotent stem cells. Blum B, Benvenisty N. Cell Cycle. 2009 Dec;8(23):3822-30.

   
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Clone- and gene-specific aberrations of parental imprinting in human induced pluripotent stem cells. Pick M, Stelzer Y, Bar-Nur O, Mayshar Y, Eden A, Benvenisty N. Stem Cells. 2009 Nov;27(11):2686-90.

   
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Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Chin MH, Mason MJ, Xie W, Volinia S, Singer M, Peterson C, Ambartsumyan G, Aimiuwu O, Richter L, Zhang J, Khvorostov I, Ott V, Grunstein M, Lavon N, Benvenisty N, Croce CM, Clark AT, Baxter T, Pyle AD, Teitell MA, Pelegrini M, Plath K, Lowry WE. Cell Stem Cell. 2009 Jul 2;5(1):111-23.

   
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Developmental programming of CpG island methylation profiles in the human genome. Straussman R, Nejman D, Roberts D, Steinfeld I, Blum B, Benvenisty N, Simon I, Yakhini Z, Cedar H. Nat Struct Mol Biol. 2009 May;16(5):564-71.

   
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The anti-apoptotic gene survivin contributes to teratoma formation by human embryonic stem cells. Blum B, Bar-Nur O, Golan-Lev T, Benvenisty N. Nat Biotechnol. 2009 Mar;27(3):281-7.

   
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Studying early lethality of 45,XO (Turner's syndrome) embryos using human embryonic stem cells. Urbach A, Benvenisty N. PLoS One. 2009;4(1):e4175.

   
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Genetic analysis of the role of the reprogramming gene LIN-28 in human embryonic stem cells. Darr H, Benvenisty N. Stem Cells. 2009 Feb;27(2):352-62.

2008

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The tumorigenicity of human embryonic stem cells. Blum B, Benvenisty N. Adv Cancer Res. 2008;100:133-58.

   
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Derivation of euploid human embryonic stem cells from aneuploid embryos. Lavon N, Narwani K, Golan-Lev T, Buehler N, Hill D, Benvenisty N. Stem Cells. 2008 Jul;26(7):1874-82.

   
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Fibroblast growth factor 4 and its novel splice isoform have opposing effects on the maintenance of human embryonic stem cell self-renewal. Mayshar Y, Rom E, Chumakov I, Kronman A, Yayon A, Benvenisty N. Stem Cells. 2008 Mar;26(3):767-74.

2007

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Developmental study of fragile X syndrome using human embryonic stem cells derived from preimplantation genetically diagnosed embryos. Eiges R, Urbach A, Malcov M, Frumkin T, Schwartz T, Amit A, Yaron Y, Eden A, Yanuka O, Benvenisty N, Ben-Yosef D. Cell Stem Cell. 2007 Nov;1(5):568-77.

   
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Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. International Stem Cell Initiative, Nat Biotechnol. 2007 Jul;25(7):803-16.

   
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Clonal analysis of human embryonic stem cell differentiation into teratomas. Blum B, Benvenisty N. Stem Cells. 2007 Aug;25(8):1924-30.

   
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Ethics. The ISSCR guidelines for human embryonic stem cell research. Daley GQ, Ahrlund Richter L, Auerbach JM, Benvenisty N, Charo RA, Chen G, Deng HK, Goldstein LS, Hudson KL, Hyun I, Junn SC, Love J, Lee EH, McLaren A, Mummery CL, Nakatsuji N, Racowsky C, Rooke H, Rossant J, Schöler HR, Solbakk JH, Taylor P, Trounson AO, Weissman IL, Wilmut I, Yu J, Zoloth L. Science. 2007 Feb 2;315(5812):603-4.

   
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Molecular analysis of LEFTY-expressing cells in early human embryoid bodies. Dvash T, Sharon N, Yanuka O, Benvenisty N. Stem Cells. 2007 Feb;25(2):465-72.

2006

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Human embryonic stem cells as a powerful tool for studying human embryogenesis. Dvash T, Ben-Yosef D, Eiges R. Pediatr Res. 2006 Aug;60(2):111-7.

   
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Human embryonic stem cells: the battle between self-renewal and differentiation. Darr H, Benvenisty N. Regen Med. 2006 May;1(3):317-25.

   
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Human embryonic stem cells as a cellular model for human disorders. Friedrich Ben-Nun I, Benvenisty N. Mol Cell Endocrinol. 2006 Jun 27;252(1-2):154-9.

   
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The effect of overexpression of Pdx1 and Foxa2 on the differentiation of human embryonic stem cells into pancreatic cells. Lavon N, Yanuka O, Benvenisty N. Stem Cells. 2006 Aug;24(8):1923-30.

   
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Overexpression of NANOG in human ES cells enables feeder-free growth while inducing primitive ectoderm features. Darr H, Mayshar Y, Benvenisty N. Development. 2006 Mar;133(6):1193-201.

   
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Factors involved in self-renewal and pluripotency of embryonic stem cells. Darr H, Benvenisty N. Handb Exp Pharmacol. 2006;(174):1-19.

   
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Human embryonic stem cells and their differentiated derivatives are less susceptible to immune rejection than adult cells. Drukker M, Katchman H, Katz G, Even-Tov Friedman S, Shezen E, Hornstein E, Mandelboim O, Reisner Y, Benvenisty N. Stem Cells. 2006 Feb;24(2):221-9.

2005

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Manipulation of the human genome in human embryonic stem cells. Kopper O, Benvenisty N.
Stem Cell Rev. 2005;1(2):145-50.

   
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Study of hepatocyte differentiation using embryonic stem cells. Lavon N, Benvenisty N.
J Cell Biochem. 2005 Dec 15;96(6):1193-202.

   
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The International Stem Cell Initiative: toward benchmarks for human embryonic stem cell research. Andrews PW, Benvenisty N, McKay R, Pera MF, Rossant J, Semb H, Stacey GN; Steering Committee of the International Stem Cell Initiative. Nat Biotechnol. 2005 Jul;23(7):795-7.

2004

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Human embryonic stem cells as a model for early human development. Dvash T, Benvenisty N.
Best Pract Res Clin Obstet Gynaecol. 2004 Dec;18(6):929-40.

   
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Temporal gene expression during differentiation of human embryonic stem cells and embryoid bodies. Dvash T, Mayshar Y, Darr H, McElhaney M, Barker D, Yanuka O, Kotkow KJ, Rubin LL, Benvenisty N, Eiges R. Hum Reprod. 2004 Dec;19(12):2875-83.

   
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Gene trap as a tool for genome annotation and analysis of X chromosome inactivation in human embryonic stem cells. Dhara SK, Benvenisty N. Nucleic Acids Res. 2004 Jul 29;32(13):3995-4002.

   
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Modeling for Lesch-Nyhan disease by gene targeting in human embryonic stem cells.
Urbach A, Schuldiner M, Benvenisty N. Stem Cells. 2004;22(4):635-41.

   
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Differentiation and isolation of hepatic-like cells from human embryonic stem cells.
Lavon N, Yanuka O, Benvenisty N. Differentiation. 2004 Jun;72(5):230-8.

   
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The "brainy side" of human embryonic stem cells. Hornstein E, Benvenisty N.
J Neurosci Res. 2004 Apr 15;76(2):169-73.

   
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The immunogenicity of human embryonic stem-derived cells. Drukker M, Benvenisty N.
Trends Biotechnol. 2004 Mar;22(3):136-41.

2003

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Factors controlling human embryonic stem cell differentiation. Schuldiner M, Benvenisty N.
Methods Enzymol. 2003;365:446-61.

   
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Selective ablation of human embryonic stem cells expressing a "suicide" gene.
Schuldiner M, Itskovitz-Eldor J, Benvenisty N. Stem Cells. 2003;21(3):257-65.

   
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Differentiation and genetic manipulation of human embryonic stem cells and the analysis of the cardiovascular system. Lavon N, Benvenisty N. Trends Cardiovasc Med. 2003 Feb;13(2):47-52.

2002

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A molecular view on pluripotent stem cells. Eiges R, Benvenisty N.
FEBS Lett. 2002 Oct 2;529(1):135-41. Review.

   
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Integration and differentiation of human embryonic stem cells transplanted to the chick embryo. Goldstein RS, Drukker M, Reubinoff BE, Benvenisty N. Dev Dyn. 2002 Sep;225(1):80-6.

   
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Characterization of the expression of MHC proteins in human embryonic stem cells. Drukker M, Katz G, Urbach A, Schuldiner M, Markel G, Itskovitz-Eldor J, Reubinoff B, Mandelboim O, Benvenisty N.
Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):9864-9.

   
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Europe and the stem cell debate. Benvenisty N.
Trends Biotechnol. 2002 May;20(5):183.

2001

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Induced neuronal differentiation of human embryonic stem cells. Schuldiner M, Eiges R, Eden A, Yanuka O, Itskovitz-Eldor J, Goldstein RS, Benvenisty N. Brain Res. 2001 Sep 21;913(2):201-5.

   
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Establishment of human embryonic stem cell-transfected clones carrying a marker for undifferentiated cells. Eiges R, Schuldiner M, Drukker M, Yanuka O, Itskovitz-Eldor J, Benvenisty N. Curr Biol. 2001 Apr 3;11(7):514-8.

2000

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Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells. Schuldiner M, Yanuka O, Itskovitz-Eldor J, Melton DA, Benvenisty N.
Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11307-12.

   
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Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers. Itskovitz-Eldor J, Schuldiner M, Karsenti D, Eden A, Yanuka O, Amit M, Soreq H, Benvenisty N. Mol Med. 2000 Feb;6(2):88-95.